This course is to introduce students to factual knowledge about Medicinal Chemistry, drug-enzyme and drug-receptor interactions, including the design and types of agonists, antagonists, inverse agonists, and partial agonists, types of inhibitors, qualitative structure-activity relationships (SAR), quantitative structure-activity relationships (QSAR). Case studies about qualitative and quantitative optimization of lead molecules. The medicinal chemistry aspects of metabolic biotransformation of drugs are covered in this course. Furthermore, providing information on the medicinal chemistry the cardiovascular agents, drugs used for the respiratory tract, and antibiotics. This course covers classes of therapeutic agents such as angiotensin-converting enzyme (ACE) inhibitors, antianginal, and antiarrhythmic inhibitors.
- Teacher: Zhawen Noori